Icenticaftor

Vendor: Abmole

Type: Molecular

SKU: M21140

$517.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Icenticaftor (QBW251) is an oral enhancer of the cystic fibrosis transmembrane conductance regulator (CFTR) channel with an EC50 of 79 nM for F508del and 497 nM for G551D CFTR. Icenticaftor can be used in chronic obstructive pulmonary disease (COPD) and cystic fibrosis studies.
Casnumber
1334546-77-8
Formula
C12H13F6N3O3
Mw
361.24
Psmiles
CC(CNC(=O)C1=C(C=C(C(=N1)OC)C(F)(F)F)N)(C(F)(F)F)O
Purity
>99%
Solubility
DMSO ≥ 100 mg/mL
Target synonyms
QBW251
Icenticaftor

Icenticaftor

$517.50 USD