IDH-305

Vendor: Abmole

Type: Molecular

SKU: M10335

$1,265.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1(R132) mutation with IC50 values of 27 nM, 28 nM and 6.14 μM for IDH1R132H, IDH1R132C and IDH1WT, respectively.
Casnumber
1628805-46-8
Formula
C23H22F4N6O2
Mw
490.45
Psmiles
CC1=CC(=NC=C1C2=CC(=NC=C2)C(F)(F)F)C(C)NC3=NC=CC(=N3)N4C(COC4=O)C(C)F
Purity
>99%
Solubility
DMSO 90 mg/mL
Target synonyms
IDH305
IDH-305

IDH-305

$1,265.00 USD