IL-1RII rabbit pAb

Name: IL-1RII rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES4200

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

[Isoform Short]: Secreted .; [Isoform Long]: Cell membrane; Single-pass type I membrane protein.

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

7850

Human swiss prot no

P27930

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human IL1R2. AA range:141-190

Isotype

IgG

Observed band

43kD

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012],

IL-1RII rabbit pAb

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