ILF2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11916
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Nucleus, nucleolus. Cytoplasm . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3608
Human swiss prot no
Q12905
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
42kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014],
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More Info
More Info
ILF2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
