Ilginatinib hydrochloride

Vendor: Abmole

Type: Molecular

SKU: M28015

$345.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).
Casnumber
1239358-85-0
Formula
C21H21ClFN7
Mw
425.89
Psmiles
CC(C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C.Cl
Purity
≥98.5%
Solubility
DMSO ≥ 35 mg/mL (ultrasonic)
Target synonyms
NS-018 hydrochloride
Ilginatinib hydrochloride

Ilginatinib hydrochloride

$345.00 USD