IMR-1

Vendor: Abmole

Type: Molecular

SKU: M8679

$109.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
IMR-1 is a first-in-class, cell-permeable inhibitor of the Notch transcription activation complex, with an IC50 of 26 μM. IMR-1 prevents Maml1 from recruiting to the Notch ternary complex (NTC) in chromatin, inhibits transcription of Notch target genes, and has antitumor activity.
Casnumber
310456-65-6
Formula
C15H15NO5S2
Mw
353.41
Psmiles
CCOC(=O)COC1=CC=C(C=C1OC)\C=C2/SC(=S)NC2=O
Purity
>98.5%
Solubility
DMSO 90 mg/mL
IMR-1

IMR-1

$109.25 USD