IMT1

Vendor: Abmole

Type: Molecular

SKU: M11519

$442.75 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
IMT1 is the first, specific and non-competitive inhibitor of human mitochondrial RNA polymerase (POLRMT). IMT1 induces conformational changes in POLRMT that block substrate binding and transcription in a dose-dependent manner in vitro. IMT1 reduced deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in significant depletion of cellular amino acid levels.
Casnumber
2304621-31-4
Formula
C21H21NO4
Mw
351.4
Psmiles
CC(OC1=CC=C2C(=C1)OC(=O)C=C2C3=C(C)C=CC=C3)C(=O)N(C)C
Purity
>98%
Solubility
DMSO ≥ 40 mg/mL
IMT1

IMT1

$442.75 USD