INCB18424

Vendor: Abmole

Type: Molecular

SKU: M1787

$287.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Ruxolitinib (INCB018424) is a first-in-class, potent, selective JAK1/2 inhibitor with an IC50 of 3.3 nM/2.8 nM. It is more than 130-fold more selective for JAK1, JAK2, and JAK3 than JAK3. It can be used in studies related to pemphigus, myelofibrosis and vitiligo.
Casnumber
941678-49-5
Formula
C17H18N6
Mw
306.37
Psmiles
N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4
Purity
99.93%
Solubility
DMSO 60 mg/mL
Target synonyms
Ruxolitinib
INCB18424

INCB18424

$287.50 USD