תמונת ברירת מחדל

Insulin R rabbit pAb

Vendor: ELK Biotechnology

SKU: ES5912

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
IHC;IF;WB;ELISA
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Late endosome . Lysosome . Binding of insulin to INSR induces internalization and lysosomal degradation of the receptor, a means for down-regulating this signaling pathway after stimulation. In the presence of SORL1, internalized INSR molecules are redirected back to the cell surface, thereby preventing their lysosomal catabolism and strengthening insulin signal reception. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3643
Human swiss prot no
P06213
Immunogen
The antiserum was produced against synthesized peptide derived from human IR. AA range:1326-1375
Isotype
IgG
Observed band
155kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;;Pig
Recommended dilutions
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
תמונת ברירת מחדל

Insulin R rabbit pAb

$148.00 USD