IOD2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11834
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Membrane ; Single-pass membrane protein .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1734
Human swiss prot no
Q92813
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
30kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
deiodinase, iodothyronine type II(DIO2) Homo sapiens The protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5'-tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3'-triiodothyronine, T3) by outer ring 5'-deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid hormone action in these tissues. It has also been reported to be highly expressed in thyroids of patients with Graves disease, and in follicular adenomas. The intrathyroidal T4 to T3 conversion by this enzyme may contribute significantly to the relative increase in thyroidal T3 production in these patients. This protein is a selenoprotein containing the rare selenocysteine (Sec) amino acid at its active site, and may
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Product Citations
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More Info
More Info
IOD2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
