Irinotecan

Vendor: Abmole

Type: Molecular

SKU: M4465

$100.05 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Irinotecan is an inhibitor of Topoisomerase I, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. Irinotecan inhibits the growth of LoVo and HT-29 cells, with IC50s of 15.8 ± 5.1 and 5.17 ± 1.4 μM, respectively.
Casnumber
97682-44-5
Formula
C33H38N4O6
Mw
586.68
Psmiles
CCC1=C2C=C(OC(=O)N3CCC(CC3)N4CCCCC4)C=CC2=NC5=C1CN6C(=O)C7=C(C=C56)C(O)(CC)C(=O)OC7
Purity
99.58%
Solubility
DMSO ≥ 20 mg/mL
Target synonyms
(+)-Irinotecan; CPT-11; VAL-413
Irinotecan

Irinotecan

$100.05 USD