Ivarmacitinib

Vendor: Abmole

Type: Molecular

SKU: M28457

$1,035.00 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects.
Casnumber
1445987-21-2
Formula
C18H22N8O2S
Mw
414.48
Psmiles
CN(C1CC2CN(CC2C1)C(=O)NC3=NC(=NS3)OC)C4=NC=NC5=C4C=CN5
Purity
≥99.0%
Solubility
DMSO 31.25 mg/mL (ultrasonic)
Target synonyms
SHR0302
Ivarmacitinib

Ivarmacitinib

$1,035.00 USD