JAB1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES2654
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . Nuclear localization is diminished in the presence of IFIT3. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
10987
Human swiss prot no
Q92905
Immunogen
The antiserum was produced against synthesized peptide derived from human COPS5. AA range:161-210
Isotype
IgG
Observed band
38kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008],
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More Info
More Info
JAB1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
