JAM-A rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4209
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell junction, tight junction . Cell membrane ; Single-pass type I membrane protein . Localized at tight junctions of both epithelial and endothelial cells. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
50848
Human swiss prot no
Q9Y624
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human F11R. AA range:191-240
Isotype
IgG
Observed band
32kD
Product weight
0.005kg
Reactivity
Human;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008],
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Product Citations
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More Info
More Info
JAM-A rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
