JKE-1674

Vendor: Abmole

Type: Molecular

SKU: M10586

$217.35 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210. JKE-1674 reduces viability of LOX-IMVI cancer cells and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1.
Casnumber
2421119-60-8
Formula
C20H20Cl2N4O4
Mw
451.30
Psmiles
ON=C(C[N](=O)=O)C(=O)N1CCN(CC1)C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3
Purity
>99.0%
Solubility
DMSO 60 mg/mL
Target synonyms
JKE1674
JKE-1674

JKE-1674

$217.35 USD