JNJ-28583113

Vendor: Abmole

Type: Molecular

SKU: M31419

$552.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
JNJ-28583113 is a brain-permeable TRPM2 antagonist and blocks phosphorylation of GSK3α and β subunits by inhibiting TRPM2. In addition, JNJ-28583113 inhibits cytokine release from microglia in response to pro-inflammatory stimuli. It has the function of protecting cells from oxidative stress-induced cell death.
Casnumber
2765255-93-2
Formula
C19H21F3N2O2
Mw
366.38
Psmiles
CCOC(=O)CN1C2=C(CCCCC2)C(=N1)C3=CC=C(C=C3)C(F)(F)F
Purity
>98.0%
Solubility
DMSO 100 mg/mL
JNJ-28583113

JNJ-28583113

$552.00 USD