JNJ-63576253

Vendor: Abmole

Type: Molecular

SKU: M10958

$161.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
JNJ-63576253 (TRC-253) is a potent and orally active complete antagonist of the androgen receptor against F877L mutant AR and wild-type AR in LNCaP cells IC50 The values are 37 and 54 nM, respectively. JNJ-63576253 can be used in the study of castration-resistant prostate cancer (CRPC).
Casnumber
2110428-64-1
Formula
C23H22ClF3N6O2S
Mw
538.97
Psmiles
Cl.FC(F)(F)C1=CC(=CN=C1C#N)N2C(=O)C3(CCC3)N(C2=S)C4=CN=C(OC5CCNCC5)C=C4
Purity
>99.0%
Solubility
DMSO ≥ 60 mg/mL
Target synonyms
TRC-253
JNJ-63576253

JNJ-63576253

$161.00 USD