JPE-1375

Vendor: Abmole

Type: Molecular

SKU: M58630

$299.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
JPE-1375 is a complement C5a receptor 1 (C5aR1) antagonist. JPE-1375 effectively inhibits polymorphonuclear leukocyte mobilization (EC50=6.9 µM) and reduces TNF levels (EC50=4.5 µM) in mice.
Casnumber
1254036-23-1
Formula
C49H63FN10O9
Mw
955.08
Psmiles
CC(C)CCC(C(=O)NC(CC1=CC=C(C=C1)F)C(=O)NC(CC2=CC=CC=C2)C(=O)N)NC(=O)C3CCCN3C(=O)C(CCCN)NC(=O)C(CC4=CC=CC=C4)NC(=O)C5CC(=O)NC(=O)N5
Purity
≥99.0%
Solubility
DMSO 96 mg/mL
JPE-1375

JPE-1375

$299.00 USD