(+)-JQ1

(+)-JQ1

Vendor: Abmole

Type: Molecular

SKU: M2167

$82.80 USD
$82.80 USD
Shipping calculated at checkout.

Available in stock (500)

Size: 10mg
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
(+)-JQ1 is a BET bromodomain inhibitor that acts on BRD4(2) with an IC50 of 33 nM and binds to all bromodomain domains in the BET family, but not to bromodomain domains outside the BET family. JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway, and JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway.
Casnumber
1268524-70-4
Formula
C23H25ClN4O2S
Mw
456.99
Psmiles
CC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(=O)OC(C)(C)C)N=C2C4=CC=C(Cl)C=C4)C
Purity
>99.0%
Solubility
DMSO 45 mg/mL; Ethanol 45 mg/mL
Target synonyms
JQ1
(+)-JQ1

(+)-JQ1

$82.80 USD
$82.80 USD