JW 74

Vendor: Abmole

Type: Molecular

SKU: M6855

$103.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
JW 74 is a wnt pathway inhibitor, with an IC50 of 420 nM. JW 74 targets the β-catenin destruction complex (GSK-3 beta /AXIN/APC). JW 74 increases AXIN2 and decreases active β-catenin levels in colorectal cancer (CRC) cells.
Casnumber
863405-60-1
Formula
C24H20N6O2S
Mw
456.52
Psmiles
COC1=CC=C(C=C1)[N]2C(=NN=C2C3=CC=NC=C3)SCC4=NC(=NO4)C5=CC=C(C)C=C5
Purity
>99.0%
Solubility
DMSO 45 mg/mL
JW 74

JW 74

$103.50 USD