K145 hydrochloride

Vendor: Abmole

Type: Molecular

SKU: M3719

$948.75 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
K145 Hydrochloride is a selective, substrate competitive and oral inhibitor of SphK2, IC50 4.3 µM and Ki 6.4 µM. K145 hydrochloride has no activity against SphK1 and other protein kinases. K145 Hydrochloride induces apoptosis and has strong anti-tumor activity.
Casnumber
1449240-68-9
Formula
C18H24N2O3S.HCl
Mw
384.92
Psmiles
CCCCOC1=CC=C(C=C1)CCC=C2C(=O)N(C(=O)S2)CCN.Cl
Purity
>99%
Solubility
Water 90 mg/mL; DMSO 40 mg/mL
Target synonyms
SphK2 inhibitor
K145 hydrochloride

K145 hydrochloride

$948.75 USD