תמונת ברירת מחדל

KGA-2727

Vendor: Abmole

Type: Molecular

SKU: M20730

$621.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
KGA-2727 is a potent, selective, high-affinity inhibitor of sodium glucose cotransporter 1 (SGLT1) with Ki of 97.4 nM and 43.5 nM for human SGLT1 and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 exhibits antidiabetic efficacy in rodent models.
Casnumber
666842-36-0
Formula
C26H40N4O8
Mw
536.62
Psmiles
CC(C)C1=C(CC2=C(C)C=C(OCCCNCCC(N)=O)C=C2)C(=N[NH]1)OC3OC(CO)C(O)C(O)C3O
Purity
>98.5%
Solubility
DMSO 100 mg/mL; Water 100 mg/mL
תמונת ברירת מחדל

KGA-2727

$621.00 USD