KI2L4 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11166
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell membrane; Single-pass type I membrane protein. Early endosome membrane .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3805
Human swiss prot no
Q99706
Immunogen
Synthesized peptide derived from human protein . at AA range: 280-360
Isotype
IgG
Observed band
41kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
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Documents
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Product Citations
Product Citations
More Info
More Info
KI2L4 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
