KIR3.1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES6005
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC
Cellular localization
Membrane; Multi-pass membrane protein.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3760
Human swiss prot no
P48549
Immunogen
The antiserum was produced against synthesized peptide derived from human GIRK1/KIR3.1/KCNJ3. AA range:151-200
Isotype
IgG
Observed band
56kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000;IHC-p 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, at
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More Info
More Info
KIR3.1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
