KL-11743

Vendor: Abmole

Type: Molecular

SKU: M28266

$529.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death.
Casnumber
1369452-53-8
Formula
C30H30N6O3
Mw
522.6
Psmiles
CCOC1=CC2=C(C=C1)N=C(N=C2NC3=CC=C(C=C3)C4=CNN=C4)C5=CC(=CC=C5)OCC(=O)NC(C)C
Purity
>99.0%
Solubility
DMSO 25 mg/mL (ultrasonic and warming and heat to 60°C)
KL-11743

KL-11743

$529.00 USD