KP-457

Vendor: Abmole

Type: Molecular

SKU: M58661

$138.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with IC50 of 11.1 nM (cell-free assay). KP-457 also cleaves various molecules such as GPIbα, GPV, and TNF-α.
Casnumber
1365803-52-6
Formula
C21H24N2O7S2
Mw
480.55
Psmiles
CC#CCOC1=CC=C(C=C1)S(=O)(=O)CC(C2=CC=C(C=C2)CNS(=O)(=O)C)N(C=O)O
Purity
≥99.0%
Solubility
DMSO 95 mg/mL
Target synonyms
KP457
KP-457

KP-457

$138.00 USD