KY02111

Vendor: Abmole

Type: Molecular

SKU: M2800

$74.75 USD
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Documents

Coa

Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
KY02111 is a widely used small molecule that boosts cardiomyogenesis. Chemical genetics of KY02111 identified squalene synthase (SQS) as a molecular target of KY02111. By disrupting the interaction of SQS with cardiac ER-membrane protein TMEM43, KY02111 impairs TGFβ/SMAD signaling and recapitulates the clinical mutation of TMEM43 that causes an inherited heart disease.
Casnumber
1118807-13-8
Formula
C18H17ClN2O3S
Mw
376.86
Psmiles
COC1=CC=C(CCC(=O)NC2=NC3=CC=C(Cl)C=C3S2)C=C1OC
Purity
≥99.0%
Solubility
DMSO 30 mg/mL
KY02111

KY02111

$74.75 USD