L-745870

Vendor: Abmole

Type: Molecular

SKU: M28637

$126.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors.
Casnumber
158985-00-3
Formula
C18H19ClN4
Mw
326.82
Psmiles
C1CN(CCN1CC2=CNC3=C2C=CC=N3)C4=CC=C(C=C4)Cl
Purity
≥99.0%
Solubility
DMSO 25 mg/mL (ultrasonic)
L-745870

L-745870

$126.50 USD