LC-2

Vendor: Abmole

Type: Molecular

SKU: M10385

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$333.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
LC-2

LC-2

$333.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
LC-2 is a potent first-in-class PROTAC capable of degrading endogenous KRAS G12C, with DC50s between 0.25 and 0.76 μM.
Casnumber
2502156-03-6
Formula
C59H71ClFN11O7S
Mw
1132.78
Psmiles
CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)CCOCCCN4CCCC4COC5=NC6=C(CCN(C6)C7=CC=CC8=C7C(=CC=C8)Cl)C(=N5)N9CCN(C(C9)CC#N)C(=O)C(=C)F)O
Purity
>98.0%
Solubility
DMSO ≥ 30 mg/mL
Technical documents

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