LCL161

Vendor: Abmole

Type: Molecular

SKU: M4801

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$172.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
LCL161

LCL161

$172.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
LCL161 is an orally bioavailable SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). LCL161 enhanced the proapoptotic effects of nilotinib and PKC412, against leukemic disease in vitro and potentiated the activity of both kinase inhibitors against leukemic disease in vivo.
Casnumber
1005342-46-0
Formula
C26H33FN4O3S
Mw
500.63
Psmiles
CNC(C)C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C3=NC(=CS3)C(=O)C4=CC=C(F)C=C4
Purity
99.70%
Solubility
DMSO 100 mg/mL
Target synonyms
LCL-161
Technical documents

Documents

Coa

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