LDE225

Vendor: Abmole

Type: Molecular

SKU: M2338

$97.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
LDE225 (NVP-LDE225; Sonidegib) is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
Casnumber
956697-53-3
Formula
C26H26F3N3O3
Mw
485.5
Psmiles
CC1CN(CC(C)O1)C2=CC=C(NC(=O)C3=C(C)C(=CC=C3)C4=CC=C(OC(F)(F)F)C=C4)C=N2
Purity
100.00%
Solubility
DMSO 60 mg/mL; Ethanol 50 mg/mL
Target synonyms
Sonidegib; NVP-LDE225; Erismodegib
LDE225

LDE225

$97.75 USD