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LDE225

LDE225

Regular price $97.75 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
LDE225 (NVP-LDE225; Sonidegib) is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
Casnumber
956697-53-3
Formula
C26H26F3N3O3
Mw
485.5
Psmiles
CC1CN(CC(C)O1)C2=CC=C(NC(=O)C3=C(C)C(=CC=C3)C4=CC=C(OC(F)(F)F)C=C4)C=N2
Purity
100.00%
Solubility
DMSO 60 mg/mL; Ethanol 50 mg/mL
Target synonyms
Sonidegib; NVP-LDE225; Erismodegib
Technical documents

Documents

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