LDN-193189 dihydrochloride

Vendor: Abmole

Type: Molecular

SKU: M2805

$126.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
LDN-193189 dihydrochloride is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, 200-fold selectivity for BMP versus TGF-β.
Casnumber
1435934-00-1
Formula
C25H24Cl2N6
Mw
479.40
Psmiles
Cl.C1CN(CCN1)C2=CC=C(C=C2)C3=C[N]4N=CC(=C4N=C3)C5=CC=NC6=C5C=CC=C6
Purity
100.00%
Solubility
Water 11 mg/mL; DMSO 8 mg/mL (ultrasonic and warming)
Target synonyms
DM-3189 dihydrochloride
LDN-193189 dihydrochloride

LDN-193189 dihydrochloride

$126.50 USD