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Lestaurtinib

Lestaurtinib

Regular price $368.00 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Lestaurtinib is a potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM, respectively). Lestaurtinib also inhibits Aurora kinase A and B (IC50 values are 8.1 and 2.3 nM, respectively) and prevents STAT5 phosphorylation (IC50 = 20 - 30 nM).
Casnumber
111358-88-4
Formula
C26H21N3O4
Mw
439.46
Psmiles
CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
Purity
≥99.0%
Solubility
DMSO 44 mg/mL
Target synonyms
CEP-701; KT-5555
Technical documents

Documents

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