Lifirafenib (BGB-283)

Vendor: Abmole

Type: Molecular

SKU: M10475

$241.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Lifirafenib (BGB-283) is a novel potent and selective RAF Kinase and EGFR inhibitor with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant.
Casnumber
1446090-79-4
Formula
C25H17F3N4O3
Mw
478.42
Psmiles
FC(F)(F)C1=CC=C2N=C([NH]C2=C1)C3C4OC5=CC=C(OC6=C7CCC(=O)N=C7NC=C6)C=C5C34
Purity
>98.5%
Solubility
DMSO 90 mg/mL
Target synonyms
Beigene-283
Lifirafenib (BGB-283)

Lifirafenib (BGB-283)

$241.50 USD