Lifitegrast

Vendor: Abmole

Type: Molecular

SKU: M5852

$322.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Lifitegrast is an antagonist of integrin lymphocyte function associated antigen-1 (LFA-1). The IC50 of Jurkat T cells to icAM-1 was 2.98nM. Lifitegrast blocks the interaction between LFA-1 and ICAM-1, thereby reducing T cell activity and cytokine secretion.
Casnumber
1025967-78-5
Formula
C29H24Cl2N2O7S
Mw
615.48
Psmiles
C[S](=O)(=O)C1=CC=CC(=C1)CC(NC(=O)C2=C(Cl)C=C3CN(CCC3=C2Cl)C(=O)C4=CC=C5C=COC5=C4)C(O)=O
Purity
99.81%
Solubility
29 mg/mL in DMSO
Target synonyms
SAR 1118; SHP-606
Lifitegrast

Lifitegrast

$322.00 USD