Lifitegrast sodium

Vendor: Abmole

Type: Molecular

SKU: M45151

$379.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Lifitegrast sodium is a potent integrin antagonist that blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen (LFA-1) and interrupts the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits the attachment of Jurkat T cells to ICAM-1 with an IC50 of 2.98 nM.May be useful in studies related to dry eye.
Casnumber
1119276-80-0
Formula
C29H23Cl2N2NaO7S
Mw
637.46
Psmiles
CS(=O)(=O)C1=CC=CC(=C1)CC(C(=O)[O-])NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl.[Na+]
Purity
>99.0%
Solubility
Water 100 mg/mL; DMSO 100 mg/mL
Target synonyms
SAR 1118 sodium; SHP-606 sodium
Lifitegrast sodium

Lifitegrast sodium

$379.50 USD