LLY-283

Vendor: Abmole

Type: Molecular

SKU: M6312

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$195.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
LLY-283

LLY-283

$195.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
LLY-283 is the potent and selective SAM-competitive chemical probe for PRMT5. It inhibits PRMT5 enzyme activity with IC50 of 20 nM for methylation of an H4R3 derived peptide substrate, and shows greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets.
Casnumber
2040291-27-6
Formula
C17H18N4O4
Mw
342.35
Psmiles
NC1=NC=NC2=C1C=C[N]2C3OC(C(O)C3O)C(O)C4=CC=CC=C4
Purity
>99.0%
Solubility
10 mM in DMSO
Technical documents

Documents

Coa

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