Lorlatinib (PF-06463922)

Vendor: Abmole

Type: Molecular

SKU: M3975

$103.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Lorlatinib (PF-06463922) is an oral active, selective, brain osmotic and ATP-competitive ROS1/ALK inhibitor. The Ki of Lorlatinib for ROS1, wild-type ALK and ALK(L1196M) were <0.025 nM, <0.07 nM and 0.7 nM, respectively. Lorlatinib has anticancer activity.
Casnumber
1454846-35-5
Formula
C21H19FN6O2
Mw
406.41
Psmiles
CC1OC2=C(N)N=CC(=C2)C3=C(C#N)[N](C)N=C3CN(C)C(=O)C4=C1C=C(F)C=C4
Purity
99.52%
Solubility
DMSO 60 mg/mL (ultrasonic and warming)
Target synonyms
PF-06463922
Lorlatinib (PF-06463922)

Lorlatinib (PF-06463922)

$103.50 USD