LRRK2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10815
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF
Cellular localization
Cytoplasmic vesicle . Perikaryon . Golgi apparatus membrane ; Peripheral membrane protein . Cell projection, axon . Cell projection, dendrite . Endoplasmic reticulum membrane ; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Endosome . Lysosome . Mitochondrion outer membrane ; Peripheral membrane protein . Colocalized with RAB29 along tubular structures emerging from Golgi apparatus (PubMed:23395371). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:25201882). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
120892
Human swiss prot no
Q5S007
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
277kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
IHC-p 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008],
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Product Citations
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More Info
More Info
LRRK2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

