LY2886721

Vendor: Abmole

Type: Molecular

SKU: M1987

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$86.25 USD
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For research use only — not intended for clinical or diagnostic purposes.
LY2886721

LY2886721

$86.25 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
LY2886721 is an effective, selective, orally active inhibitor of beta-site amyloid precursor protein lyase 1 (BACE1) with an IC50 of 20.3 nM against recombinant human BACE1. LY2886721 showed higher selectivity for BACE1 than cathepsin D, pepsin and renin, but lacked selectivity for BACE2 (IC50 was 10.2 nM). LY2886721 crosses the blood-brain barrier and can be used to study Alzheimer's disease.
Casnumber
1262036-50-9
Formula
C18H16F2N4O2S
Mw
390.41
Psmiles
NC1=NC2(COCC2CS1)C3=CC(=CC=C3F)NC(=O)C4=NC=C(F)C=C4
Purity
>99.0%
Solubility
DMSO
Technical documents

Documents

Coa

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