M-RIP rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3382
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA;IHC
Cellular localization
Cytoplasm, cytoskeleton . Colocalizes with F-actin.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
23164/23164
Human swiss prot no
Q6WCQ1
Immunogen
Synthesized peptide derived from the Internal region of human M-RIP.
Isotype
IgG
Observed band
115kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
function:Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.,similarity:Contains 1 PH domain.,similarity:Contains 2 PH domains.,subcellular location:Colocalizes with F-actin.,subunit:Binds F-actin through its N-terminus (By similarity). Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains.,
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More Info
More Info
M-RIP rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
