Macozinone

Vendor: Abmole

Type: Molecular

SKU: M28285

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$460.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Macozinone

Macozinone

$460.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Bioactivity
Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect.
Casnumber
1377239-83-2
Formula
C20H23F3N4O3S
Mw
456.48
Psmiles
FC(F)(F)C1=CC(=C2SC(=NC(=O)C2=C1)N3CCN(CC3)CC4CCCCC4)[N;v5](=O)=O
Purity
≥99.0%
Solubility
DMSO 6.4 mg/mL (ultrasonic)
Target synonyms
PBTZ169
Technical documents

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Coa

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