MBP rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8978
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic side of myelin.; [Isoform 3]: Nucleus . Targeted to nucleus in oligodendrocytes.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
4155
Human swiss prot no
P02686
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Isotype
IgG
Observed band
33kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that
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More Info
More Info
MBP rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
