MCM6 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4184
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
Request a Quote
✅ Thank you! Your quote request was sent successfully.
❌ Something went wrong. Please check your details and try again.
- Customs clearance fees may apply
- Worldwide shipping available.
Couldn't load pickup availability
For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC
Cellular localization
Nucleus . Chromosome . Binds to chromatin during G1 and detach from it during S phase. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
4175
Human swiss prot no
Q14566
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MCM6. AA range:331-380
Isotype
IgG
Observed band
90kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000;IHC-p 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, i
Documents
Documents
Documents
Product Citations
Product Citations
More Info
More Info
MCM6 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
