MCR rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11266
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein. Cytoplasmic and nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
4306
Human swiss prot no
P08235
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Isotype
IgG
Observed band
108kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
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More Info
More Info
MCR rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
