MeBIO

Vendor: Abmole

Type: Molecular

SKU: M21232

$172.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
MeBIO, an analog of 6-bromoindirubin-3'-oxime, has been suggested to possess the structural basis for a potent and selective inhibitor of glycogen synthase kinase-3 (GSK3) and cyclin-dependent kinases. MeBIO displays minimal activity against CDK1/Cyclin B, GSK-3, and CDK5/p25 (IC50 values are 92.0, 44-100 and >100 μM respectively). MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist.
Casnumber
667463-95-8
Formula
C17H12BrN3O2
Mw
370.20
Psmiles
CN1C2=C(C=CC(=C2)Br)C(=C1O)C3=C(C4=CC=CC=C4N3)N=O
Purity
>98%
Solubility
DMSO 10 mg/mL (May need warming and ultrasonic)
Target synonyms
6-bromoindirubin-3'-oxime
MeBIO

MeBIO

$172.50 USD