Merestinib

Vendor: Abmole

Type: Molecular

SKU: M3767

$178.25 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Merestinib (LY2801653) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib (LY2801653) also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM).
Casnumber
1206799-15-6
Formula
C30H22F2N6O3
Mw
552.53
Psmiles
C[N]1N=CC2=CC(=C(C=C12)C3=C[NH]N=C3)OC4=C(F)C=C(NC(=O)C5=CC=C(C)N(C5=O)C6=CC=C(F)C=C6)C=C4
Purity
>99%
Solubility
DMSO 30 mg/mL
Target synonyms
LY2801653
Merestinib

Merestinib

$178.25 USD