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Methotrexate disodium

Methotrexate disodium

Regular price $46.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
Casnumber
7413-34-5
Formula
C20H20N8Na2O5
Mw
498.4
Psmiles
[Na+].[Na+].CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O
Purity
>99.0%
Solubility
Water 50 mg/mL; DMSO 5 mg/mL (ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C)
Target synonyms
Amethopterin disodium; CL14377 disodium; WR19039 disodium
Technical documents

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