mGluR-2/3 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES5675
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane; Multi-pass membrane protein. Cell junction, synapse . Cell projection, dendrite .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2912/2913
Human swiss prot no
Q14416/Q14832
Immunogen
The antiserum was produced against synthesized peptide derived from human mGluR2/3. AA range:823-872
Isotype
IgG
Observed band
100kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
glutamate metabotropic receptor 2(GRM2) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene
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Product Citations
Product Citations
More Info
More Info
mGluR-2/3 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
