mGluR1 rabbit pAb

Name: mGluR1 rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES5672

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

IHC;IF;ELISA

Cellular localization

Cell membrane ; Multi-pass membrane protein .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

2911

Human swiss prot no

Q13255

Immunogen

The antiserum was produced against synthesized peptide derived from human GRM1. AA range:251-300

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Mouse;Rat

Recommended dilutions

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

glutamate metabotropic receptor 1(GRM1) Homo sapiens This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],

mGluR1 rabbit pAb

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